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Filtered Search Results
eMolecules EMOLECULES INC
5000490785 ETHYL 4 4-DIFLUOROACETOACET 5G
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Medchemexpress LLC Gisadenafil besylate | 334827-98-4 | MFCD18384964 | 99.6% | 677.79 g/mol | C29H39N7O8S2 | 5 MG
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Gisadenafil besylate (CAS 334827-98-4) is an orally active phosphodiesterase 5 (PDE5) inhibitor used in biochemical and pharmacological research to prevent degradation of cyclic guanosine monophosphate (cGMP). It is employed to study PDE5-mediated signaling and pharmacology in vitro and in vivo, and is provided as a high-purity research reagent.
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eMolecules AA Blocks LLC 2-Quinolinecarboxaldehyde 250mg 704945183 AA0033D2 0 000 5470-96-2 MFCD00075032 157 172 C10H7NO
AA Blocks LLC 2-Quinolinecarboxaldehyde 250mg 704945183 AA0033D2 0 000 5470-96-2 MFCD00075032 157 172 C10H7NO
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eMolecules Combi-Blocks 2-(Difluoromethoxy)isonicotinic acid 250mg 517037643 HB-7021 98 000 1211581-51-9 MFCD18258474 189 118 C7H5F2NO3
Combi-Blocks 2-(Difluoromethoxy)isonicotinic acid 250mg 517037643 HB-7021 98 000 1211581-51-9 MFCD18258474 189 118 C7H5F2NO3
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Medchemexpress LLC PKI-179 hydrochloride | 1463510-35-1 | 99.66% | 525.00 | 500 UG
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PKI-179 hydrochloride is a potent and orally active dual PI3K/mTOR inhibitor. It shows IC50s of 8 nM, 24 nM, 74 nM, 77 nM, and 0.42 nM for PI3K-α, PI3K-β, PI3K-γ, PI3K-δ, and mTOR, respectively. It also exhibits activity over E545K and H1047R, with IC50s of 14 nM and 11 nM, respectively. PKI-179 hydrochloride has demonstrated anti-tumor activity in vivo.
- Potent and orally active dual PI3K/mTOR inhibitor.
- Exhibits activity against various PI3K isoforms (PI3K-α, PI3K-β, PI3K-γ, PI3K-δ) and mTOR.
- Active against E545K and H1047R.
- Shows anti-tumor activity in vivo.
- Inhibits cell proliferation in MDA361 and PC3 cells.
- Good oral bioavailability (98% in nude mouse, 46% in rat, 38% in monkey, and 61% in dog) and a high half-life (>60 min).
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eMolecules EMOLECULES INC
5000488391 METHYL 4-FORMYLBENZOATE 100G
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Sigma Aldrich Fine Chemicals Biosciences Ethyl arachidate 9910G
Ethyl arachidate 9910G
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eMolecules EMOLECULES INC
5000489952 4-CHLORO-2-METHYLPYRIMIDINE 1G
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eMolecules Oakwood Chemicals Cyclopropanecarbaldehyde 250mg 486558522 065337 0 000 1489-69-6 MFCD00012261 70 091 C4H6O
Oakwood Chemicals Cyclopropanecarbaldehyde 250mg 486558522 065337 0 000 1489-69-6 MFCD00012261 70 091 C4H6O
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Medchemexpress LLC AHR 10240, a cyclic amide metabolite of bromfenac | 91713-91-6 | MFCD08694315 | >98.0% | 316.15 | C15H10BrNO2 | 250 MG
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AHR 10240 is a cyclic amide metabolite of bromfenac used in analgesia research. It is described as an endogenous metabolite relevant to metabolic enzyme and protease pathways. Key chemical identifiers include CAS 91713-91-6, molecular formula C15H10BrNO2, and molecular weight 316.15.
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Medchemexpress LLC Anticaries agent-1 | 198649-97-7 | ≥97.0% | 256.25 | 250 MG
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Anticaries agent-1 (Compound 21b) is an anticaries agent. It inhibits biofilm formation (IC50: 77 μM) and *S. mutans* growth, making it suitable for research on dental health.
- Inhibits biofilm formation (IC50: 77 μM)
- Inhibits *S. mutans* growth
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Medchemexpress LLC 2,5-dioxopyrrolidin-1-yl hept-6-ynoate | 917222-23-2 | MFCD29041721 | 98.0% | 223.23 g/mol | C11H13NO4 | 250 MG
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2,5-Dioxopyrrolidin-1-yl hept-6-ynoate is an amine-reactive N-hydroxysuccinimide (NHS) ester bearing a terminal alkyne. It enables selective derivatization of primary amines on peptides, proteins, antibodies, and amine-coated surfaces and facilitates copper-catalyzed azide-alkyne cycloaddition (Click Chemistry) for bioconjugation workflows.
- Amine-reactive N-hydroxysuccinimide (NHS) ester for selective labeling of primary amines.
- Terminal alkyne enables copper-catalyzed azide-alkyne cycloaddition (Click Chemistry).
- Suitable for peptides, proteins, antibodies, and amine-coated surfaces.
- Available in small laboratory pack sizes for method development and optimization.
- Recommended storage under cool, inert conditions to maintain stability.
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Medchemexpress LLC Exatecan Intermediate 6 | 143655-58-7 | 98.98% | 235.26 | 250 MG
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Exatecan Intermediate 6 is an intermediate of Exatecan and Exatecan. It functions as a DNA topoisomerase I inhibitor, making it suitable for applications in cancer research. This compound can also be utilized for synthesizing Antibody-Drug Conjugates (ADCs).
- Functions as a DNA topoisomerase I inhibitor
- Used in cancer research
- Can be used to synthesize antibody-drug conjugates (ADCs)
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eMolecules Advanced ChemBlocks methyl 1-formylcyclobutane-1-carboxylate 250mg 816442592 P47880 97 000 155380-49-7 MFCD15526935 142 154 C7H10O3
Advanced ChemBlocks methyl 1-formylcyclobutane-1-carboxylate 250mg 816442592 P47880 97 000 155380-49-7 MFCD15526935 142 154 C7H10O3
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Medchemexpress LLC Pomalidomide 4'-alkylC5-acid | 2225940-49-6 | 98.8% | 250 MG
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Pomalidomide 4'-alkylC5-acid is an E3 ligase ligand-linker conjugate. It contains a cereblon (CRBN) ligand, which is Pomalidomide based, and a linker. This compound can be utilized in the synthesis of PROTAC (Proteolysis Targeting Chimeras). PROTACs are composed of two distinct ligands connected by a linker, where one ligand targets an E3 ubiquitin ligase and the other targets the protein of interest. These molecules function by harnessing the intracellular ubiquitin-proteasome system to achieve the selective degradation of target proteins.
- Can be utilized in the synthesis of PROTAC
- Contains a cereblon (CRBN) ligand
- Contains a linker
- Targets an E3 ubiquitin ligase
- Targets the protein of interest
- Harnesses the intracellular ubiquitin-proteasome system
- Achieves selective degradation of target proteins
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